A.P. Bio poster

A.P. Bio

2018 to 2021 Comedy 4 seasons

TMDB rating 6.9/10 Canceled

When disgraced Harvard philosophy scholar Jack Griffin loses out on his dream job, he is forced to return to Toledo, Ohio, and work as a high school Advanced Placement biology teacher.

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Seasons4

  • When Harvard philosophy scholar Jack Griffin finds himself teaching high school in Toledo, Ohio, he tosses the syllabus and recruits his students to help enact revenge on his rival.

    All episodes available

    TMDB rating 7.3/10

  • Having botched his chance to get out of Toledo last season, disgraced Harvard philosophy scholar Jack Griffin is once again stuck teaching biology class at Whitlock High for the lovable Principal Durbin.

    All episodes available

    TMDB rating 7.9/10

  • Season 3 of A.P. Bio marked the show’s transition from NBC to the streaming platform Peacock. This shift allowed the series to become more experimental, lean into its absurdist comedy, and focus less on Jack Griffin's (Glenn Howerton) desire to leave Toledo and more on his bizarre integration into Whitlock High.

    All episodes available

    TMDB rating 7.4/10

  • Season 4 of A.P. Bio continues the show's evolution into a high-energy, absurdist ensemble comedy. Released on Peacock, it focuses on Jack Griffin finally embracing his role as a chaotic mentor to his students while navigating his own unresolved family trauma.

    All episodes available

    TMDB rating 7.0/10

Cast and details

  • Glenn HowertonJack Griffin
  • Patton OswaltPrincipal Ralph Durbin
  • Lyric LewisStef
  • Mary SohnMary
  • Jean VillepiqueMichelle
  • Aparna BrielleSarika
  • Allisyn SnyderHeather
  • Eddie LeavyAnthony
  • Jacob HoustonVictor
  • Nick PeineMarcus
  • Sari ArambuloGrace
  • Spence Moore IIDan Decker
Created by
Michael Patrick O'Brien
Network
NBC, Peacock
First aired
Feb 1, 2018
Latest episode
Sep 2, 2021

PEN15

2019

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Release dates are original schedules and may differ from availability in your country. A release never marks anything as watched. Last checked Nov 3, 2026.Schedule data from TVmaze, CC BY-SA.